By Daniel Gana, MsC, Abraham Benavides, MD, and Brent Ristow, PhD, JD, 2-28-2025

By 2060, nearly a quarter of the U.S. population will be 65 or older. With aging populations comes an alarming rise in chronic health issues. Despite a lifetime of contributions to society, many seniors find themselves trapped in a heartbreaking cycle of prescriptions – taking one pill after another, while the pain persists, mobility fades, and memories continue to slip away. Instead of aging with dignity, too many are left feeling like prisoners in their own bodies.

Seniors face increasing risks of diabetes, osteoporosis, and Alzheimer’s, along with other age-related conditions such as arthritis, heart disease, high blood pressure, and vision loss. Data from the CDC shows about 29% of seniors have diabetes, while osteoporosis affects about 13% of American seniors and increases with age. 

To manage these conditions, prescription drug use is widespread. Seventy percent of adults aged 40–79 in the United States take at least one prescription drug in a given month, while around 1 in 5 take five or more prescription drugs. Overprescribing is a growing trend that raises serious concerns about dependency and adverse side effects.

As the downsides of pharmaceuticals become clearer, seniors are turning to hemp for relief. Studies show that 21% of adults aged 50+ have used hemp in the past year, with many seeking relief from pain (63%), sleep issues (68%), and mental health concerns (53%). This article explores how hemp medicine can benefit seniors and how to maximize its potential.

Potential Therapeutic Benefits of Hemp for Seniors

1. Cardiovascular Health

Research increasingly suggests that whole-plant cannabis remedies can help reduce blood pressure, thanks to the combined effects of cannabinoids like CBDA, CBGA, CBD, and THCV, along with terpenes and flavonoids.

For example, a 2021 study published in the European Journal of Internal Medicine examined the effects of cannabis oil on hypertension in seniors aged 75 and older. The study included 26 patients with an average age of 70, of whom 53.8% were women. After three months of treatment, their 24-hour systolic and diastolic blood pressure levels dropped by 5.0 mmHg and 4.5 mmHg, respectively (p<0.001). The most significant reduction in blood pressure and heart rate occurred approximately three hours after administration. Additionally, the proportion of patients with a normal dipping blood pressure pattern increased from 27.3% before treatment to 45.5% after. However, no significant changes were observed in metabolic markers, body measurements, or ECG results.

A 2023 UK Biobank study of 91,161 participants found that heavy and current cannabis use lowered blood pressure in both men and women, with stronger effects in women. Men without dyslipidemia and women who smoked or drank moderately saw the most significant reductions. However, the differences were too small to support cannabis-based hypertension policies.

Research also highlights hempseed as a rich source of omega-3 and omega-6 fatty acids, which support cardiovascular health. Recent studies, primarily in animals, suggest these compounds and dietary hempseed may help reduce platelet aggregation, lower the risk of ischemic heart disease, and improve overall heart health.

2. Chronic Pain Management

Chronic pain affects about 60% to 75% of seniors, making it one of the most prevalent conditions in this age group. It is also a leading reason for prescribing medical cannabis, with studies showing that up to 64% of medical cannabis users seek relief from chronic pain.

A survey of medical cannabis patients in Florida found that most used it to manage chronic pain or depression, followed by arthritis and nausea. Notably, 89% of patients reported “great relief” from their condition, while over 76% rated their improvement as 8 or higher on a 10-point scale. Additionally, 68% gave similar high ratings for pain reduction. Interviews further revealed that while patients found medical cannabis effective for pain relief and reducing prescription medication use, many considered it too expensive.

3. Neurodegenerative Diseases

Neurodegenerative diseases like dementia and Parkinson’s affect millions of seniors globally, robbing those individuals of independence and placing immense strain on families.

A real-life assessment study examined the effects of medical cannabis on patients with Parkinson’s disease. The research discovered a link between cannabis and improved quality of life and relief from non-motor symptoms. 

Preclinical research suggests that marijuana-based compounds may offer significant benefits for neurodegenerative diseases, thanks to their anti-inflammatory, antioxidant, and anti-excitotoxic properties.

4. Sleep Disturbances

While sleep disorders are a common concern among older adults, often leading to pain and anxiety, hemp-derived compounds such as CBD, CBG, and CBN have been studied for their potential to improve sleep quality. Additionally, terpenes like myrcene and linalool are known for their calming and sedative effects, while flavonoids such as apigenin may further promote relaxation. Together, these natural compounds offer a holistic approach to better sleep.

Information from a 2018 study identified insomnia as one of the primary reasons seniors used cannabis, along with chronic pain, depression, and anxiety. The study found that 32% of surveyed seniors had used marijuana in the past, with 16% starting after legalization. More than half of current users were 75 or older, and the majority were white women. Among users, 44% consumed marijuana at least weekly, with most reporting positive effects. However, 67% obtained marijuana recreationally rather than through a prescription, highlighting accessibility challenges in healthcare. 

What Are The Benefits Of Full-Spectrum Hemp Extracts For Seniors?

Full-spectrum hemp extracts provide distinct advantages over isolates, making them a superior choice for seniors looking for maximum effectiveness, versatility, and ease of use. Some of the reported benefits of full-spectrum hemp extracts over isolates for seniors include higher bioavailability, lower required dosages, and longer duration of effectiveness. 

1. Higher bioavailability

A 2023 study demonstrated that CBD bioavailability significantly increases when administered as a full-spectrum extract compared to CBD isolate. Researchers observed a notable rise in oral bioavailability, with CBD absorption increasing by 12% in male rats and 21% in female rats when delivered as a full-spectrum product rather than an isolate or broad-spectrum formulation.

Another study published in 2021 showed CBDA concentrations were 14 times higher in plasma when administered as part of a cannabis extract compared to when CBDA was given as an isolated compound. 

This increased bioavailability is influenced by the presence of other cannabinoids, terpenes and flavonoids. It is also important to note that full-spectrum hemp retains the plant’s natural compounds in their natural electronic configuration thus enhancing absorption, and ensuring faster and more effective results. 

Fat-soluble cannabinoids bind to natural plant compounds, increasing their ability to enter the bloodstream, while the entourage effect maximizes their impact. This synergy allows seniors to experience relief with smaller doses, reducing the need for frequent applications or high consumption.

2. Better effect at lower doses

Full-spectrum hemp extracts provide enhanced effects at lower doses due to the synergistic interaction of their active compounds. These compounds work together to increase receptor activation, slow down cannabinoid degradation, and optimize absorption, resulting in greater overall effectiveness as reported in the 2021 study which recorded 14 times more CBDA when administered as a full-spectrum. This natural synergy, known as the entourage effect, allows the body to utilize cannabinoids more efficiently, maximizing benefits without the need for high doses.

The combination of multiple active compounds provides longer-lasting relief, making it an excellent choice for pain management, sleep support, and cognitive health. Seniors can rely on full-spectrum extracts to provide sustained benefits without the need for constant reapplication or increased dosing over time. This also provides long-term cost-effectiveness benefits.

3. Longer effects

Certain flavonoids and terpenes enhance the effects of cannabinoids by slowing their degradation and increasing bioavailability. Flavonoids can inhibit metabolic enzymes like cytochrome P450 and FAAH, preventing cannabinoids from breaking down too quickly. This extends their duration in the body, leading to longer-lasting effects and improved therapeutic benefits.

Similarly, terpenes such as myrcene and beta-caryophyllene can influence cannabinoid absorption and activity. Some terpenes enhance cell membrane or blood-brain-barrier permeability, allowing cannabinoids to enter the bloodstream and brain more efficiently, while others bind to cannabinoid receptors, amplifying their effects. 

The Role of Active-Spectrum™ Hemp Extracts in Supporting Senior Health

Aging doesn’t have to mean slowing down or settling for discomfort. At any stage of life, you deserve to feel strong, energized, and clear-minded. Our Active-Spectrum™ hemp extracts are designed to help you stay active, pain-free, and mentally sharp, unlocking new possibilities for a healthier, more vibrant you.

These powerhouse extracts are crafted using a proprietary extraction process that preserves the full range of cannabinoids, terpenes, and flavonoids in their most potent and natural form. Unlike isolated compounds, these elements work synergistically in what’s known as the entourage effect and ensemble effect, enhancing absorption, boosting efficacy, and ensuring you experience the full benefits of hemp.

From pain relief and better sleep to sharper cognition and enhanced vitality, Active-Spectrum™ hemp extracts support your body at the cellular level. By activating your ECS and mitochondria, the powerhouse of your cells, they help sustain energy levels, combat inflammation, and promote overall well-being so you can continue doing what you love, without limitations.

References
–

1. Abuhasira, R., Haviv, Y. S., Leiba, M., Leiba, A., Ryvo, L., & Novack, V. (2021). Cannabis is associated with blood pressure reduction in older adults – A 24-hours ambulatory blood pressure monitoring study. European Journal of Internal Medicine, 86, 79–85. doi.org/10.1016/j.ejim.2021.01.005
2. Anderson, L. L., Etchart, M. G., Bahceci, D., Golembiewski, T. A., & Arnold, J. C. (2021). Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations. Scientific Reports, 11(1), 14948. doi.org/10.1038/s41598-021-94212-6
3. Arachchige, A. S. P. M. (2023). Marijuana’s potential in neurodegenerative diseases: An editorial. AIMS Neuroscience, 10(2), 175–177. doi.org/10.3934/Neuroscience.2023014
4. Balash, Y., Bar-Lev Schleider, L., Korczyn, A. D., Shabtai, H., Knaani, J., Rosenberg, A., Baruch, Y., Djaldetti, R., Giladi, N., & Gurevich, T. (2017). Medical Cannabis in Parkinson Disease: Real-Life Patients’ Experience. Clinical Neuropharmacology, 40(6), 268. doi.org/10.1097/WNF.0000000000000246
5. Berthold, E. C., Kamble, S. H., Kanumuri, S. R. R., Kuntz, M. A., Senetra, A. S., Chiang, Y.-H., McMahon, L. R., McCurdy, C. R., & Sharma, A. (2023). Comparative Pharmacokinetics of Commercially Available Cannabidiol Isolate, Broad-Spectrum, and Full-Spectrum Products. European Journal of Drug Metabolism and Pharmacokinetics, 48(4), 427–435. doi.org/10.1007/s13318-023-00839-3
6. Boehnke, K. F., Gangopadhyay, S., Clauw, D. J., & Haffajee, R. L. (2019). Qualifying Conditions Of Medical Cannabis License Holders In The United States. Health Affairs, 38(2), 295–302. doi.org/10.1377/hlthaff.2018.05266
7. CDC. (2019, August 8). Products—Data Briefs—Number 347—August 2019. www.cdc.gov/nchs/products/databriefs/db347.htm
8. CDC. (2021, May 13). Products—Data Briefs—Number 405—March 2021. CDC Newsroom. doi.org/10.15620/cdc:103477
9. CDC. (2024, July 23). National Diabetes Statistics Report. Diabetes. www.cdc.gov/diabetes/php/data-research/index.html
10. Gavin, K. (2024, September 12). Cannabis & older adults: Poll looks at use, beliefs and risk | Michigan Medicine. www.michiganmedicine.org/health-lab/cannabis-older-adults-poll-looks-use-beliefs-and-risk
11. Luque, J. S., Okere, A. N., Reyes-Ortiz, C. A., & Williams, P. M. (2021). Mixed methods study of the potential therapeutic benefits from medical cannabis for patients in Florida. Complementary Therapies in Medicine, 57, 102669. doi.org/10.1016/j.ctim.2021.102669
12. Mather, M., Jacobsen, L. A., & Ard, K. M. P. (2015). Population Bulletin: Aging In The United States. POPULATION BULLETIN.
13. Nawai, A. (2019). Chronic Pain Management Among Older Adults: A Scoping Review. SAGE Open Nursing. doi.org/10.1177/2377960819874259
14. Reynolds, I. R., Fixen, D. R., Parnes, B. L., Lum, H. D., Shanbhag, P., Church, S., Linnebur, S. A., & Orosz, G. (2018). Characteristics and Patterns of Marijuana Use in Community-Dwelling Older Adults. Journal of the American Geriatrics Society, 66(11), 2167–2171. doi.org/10.1111/jgs.15507
15. Rodriguez-Leyva, D., & Pierce, G. N. (2010). The cardiac and haemostatic effects of dietary hempseed. Nutrition & Metabolism, 7, 32. doi.org/10.1186/1743-7075-7-32
16. Vallée, A. (2023). Association between cannabis use and blood pressure levels according to comorbidities and socioeconomic status. Scientific Reports, 13(1), 2069. doi.org/10.1038/s41598-022-22841-6
17. Vulfsons, S., Minerbi, A., & Sahar, T. (2020). Cannabis and Pain Treatment—A Review of the Clinical Utility and a Practical Approach in Light of Uncertainty. Rambam Maimonides Medical Journal, 11(1), e0002. doi.org/10.5041/RMMJ.10385